Anti-CD25 / IL2RA (Activated Lymphocyte Marker) Monoclonal Antibody(Clone: IL2RA/2395)

Name: Anti-CD25 / IL2RA (Activated Lymphocyte Marker) Monoclonal Antibody(Clone: IL2RA/2395)
Brand: Abeomics
SKU: 36-2588
Price: 520.0000 USD
Availability: InStock
Rating: 4.8 (10 reviews)

Fig. 1: Formalin-fixed, paraffin-embedded human Tonsil stained with CD25 Mouse Monoclonal Antibody (IL2RA/2395).

Anti-CD25 / IL2RA (Activated Lymphocyte Marker) Monoclonal Antibody(Clone: IL2RA/2395)

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Fig. 1: Formalin-fixed, paraffin-embedded human Tonsil stained with CD25 Mouse Monoclonal Antibody (IL2RA/2395).

Fig. 2: Formalin-fixed, paraffin-embedded human Tonsil stained with CD25 Mouse Monoclonal Antibody (IL2RA/2395).

Fig. 3: SDS-PAGE Analysis Purified CD25 Mouse Monoclonal Antibody (IL2RA/2395). Confirmation of Purity and Integrity of Antibody.

Fig. 4: Analysis of Protein Array containing >19,000 full-length human proteins using CD25 Mouse Monoclonal Antibody (IL2RA/2395) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Product code: 36-2588

Clone name :	IL2RA/2395
Clonality :	Monoclonal
Application :	IHC
Reactivity :	Human

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For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

Amount :	100 µg
Isotype :	Mouse IgG2b, kappa
Content :	200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition :	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.


Gene :	IL2RA
Gene ID :	3559
Uniprot ID :	P01589
Alternative Name :	IL2 Receptor alpha; IL2R alpha chain; IL2R; IL2R subunit alpha IL2RA; Interleukin-2 receptor subunit alpha; Ly43; p55; p55 chain; T Cell Growth Factor Receptor; TAC antigen; TCGFR
Immunogen Information :	Recombinant fragment of human IL2RA protein (around aa 42-183) (exact sequence is proprietary)

Recognizes a protein of 55kDa, identified as CD25. It is expressed on activated T- and B-cells and activated monocytes/macrophages. With respect to lymphomas, CD25 is present on malignant cells of Hodgkin's disease, HTLV-1+ adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R chain, p75) and CD132 (common chain) to form the high affinity IL-2 receptor complex. CD25 antibodies detect three epitope regions, A, B and C. This MAb recognizes the epitope B, which is located at residue 3-104 of CD25 and doe not block IL-2 binding to CD25.

Immunohistochemistry (Formalin-fixed) (2-4ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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