Anti-CD21 Monoclonal Antibody (Clone:LT21)-PE Conjugated

Product code: 30-2198

Clone name : LT21
Clonality : Monoclonal
Application : FACS, IHC-Fr
Reactivity : Human, Pig, Bovine, Dog
Conjugate : PE

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Price
100 tests
$468.00 

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For estimated delivery dates, please contact us at [email protected]


Amount : 100 tests
Isotype : Mouse IgG1
Storage condition : Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Gene : CR2
Gene ID : 1380
Uniprot ID : P20023
Alternative Name : CR2, C3DR
Immunogen Information : IM9 human B-lymphoblastoid cell line
CD21 (complement receptor 2, CR2) binds C3 complement fragments, especially its breakdown fragments, which remain covalently attached to complement activating surfaces or antigen. CD21 has important roles in uptake and retention of immunocomplexes, survival of memory B cells and in development and maintenance of the humoral response to T-dependent antigens. CD21 also serves as a key receptor for Epstein-Barr virus binding and is involved in targeting prions to folicular dendritic cells and expediting neuroinvasion following peripheral exposure to prions. A soluble form of the CD21 (sCD21) is shed from the lymphocyte surface and retains its ability to bind respective ligands.
Subcellular location: Membrane
Tissue Specificity: Mature B-lymphocytes, T-lymphocytes, pharyngeal epithelial cells, astrocytes and follicular dendritic cells of the spleen.
BioGrid: 107771. 7 interactions.
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