Anti-CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) Monoclonal Antibody(Clone: CR2/2754)

Name: Anti-CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) Monoclonal Antibody(Clone: CR2/2754)
Brand: Abeomics
SKU: 36-2116
Price: 520.0000 USD
Availability: InStock
Rating: 4.1 (10 reviews)

Fig. 1: Formalin-fixed, paraffin-embedded human Tonsil Dendritic stained with CD21-Monospecific Mouse Monoclonal Antibody (CR2/2754).

Anti-CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) Monoclonal Antibody(Clone: CR2/2754)

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Fig. 1: Formalin-fixed, paraffin-embedded human Tonsil Dendritic stained with CD21-Monospecific Mouse Monoclonal Antibody (CR2/2754).

Fig. 2: SDS-PAGE Analysis Purified CD21-Monospecific Mouse Monoclonal Antibody (CR2/2754). Confirmation of Integrity and Purity of Antibody.

Fig. 3: Western Blot Analysis of human Raji cell lysate using CD21-Monospecific Mouse Monoclonal Antibody (CR2/2754).

Fig. 4: Flow Cytometric Analysis of PFA-fixed MOLT4 cells. CD21-Monospecific Mouse Monoclonal Antibody (CR2/2754) followed by Goat anti-Mouse IgG-CF488 (Blue); Isotype Control (Red).

Fig. 5: Immunofluorescence staining of PFA-fixed MOLT4 cells using CD21-Monospecific Mouse Monoclonal Antibody (CR2/2754) followed by goat anti-Mouse IgG conjµgated to CF488 (green). Nuclei are stained with Reddot.

Fig. 6: Analysis of Protein Array containing more than 19,000 full-length human proteins using CD21-Monospecific Mouse Monoclonal Antibody (CR2/2754) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Product code: 36-2116

Clone name :	CR2/2754
Clonality :	Monoclonal
Application :	ELISA, FACS, WB, IF, IHC
Reactivity :	Human

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Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

Amount :	100 µg
Isotype :	Mouse IgG1, kappa
Content :	200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition :	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.


Gene :	CR2
Gene ID :	1380
Uniprot ID :	P20023
Alternative Name :	CD21; Complement C3d receptor (C3DR); Complement Receptor type 2 (CR2); CVID7; EBV receptor; EBV-R; Epstein-Barr virus receptor; EVBR; SLEB9
Immunogen Information :	Recombinant fragment (around aa 142-240) of human CR2 (CD21) protein (exact sequence is proprietary)

Recognizes a protein of 140kDa, which is identified as the complement receptor 2 (CR2) or CD21. This protein is expressed strongly on mature B cells, follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro. CD21 functions as receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFNalpha. CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation.

ELISA (For coating, order antibody without BSA);,Flow Cytometry (1-2ug/million cells); Cells are fixed using 3% PFA.,Western Blot (1-2ug/ml);,Immunofluorescence (1-2ug/ml);,Immunohistology (Formalin-fixed) (1-2ug/ml for 30 min at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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