Anti-CD207 Monoclonal Antibody (Clone:2G3)

Product code: 30-2927

Clone name : 2G3
Clonality : Monoclonal
Application : ICC, ELISA, IHC, FACS
Reactivity : Human, Non-Human Primates

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0.1 mg
$389.00 

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Format : Purified
Amount : 0.1 mg
Isotype : Mouse IgG1 lambda
Purification : Purified by protein-A affinity chromatography.
Content : Formulation: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage condition : Store at 2-8°C. Do not freeze.
Gene : CD207
Gene ID : 50489
Uniprot ID : Q9UJ71
Immunogen Information : Fusion protein of human CD207 extracellular part and IgG Fc fragment

CD207 is a 40 kDa type II transmembrane glycoprotein of the C-type lectin family. It binds to mannose-bearing glycoproteins and glycolipids of microbial and viral antigens, including HIV gp120. CD207 is expressed only in Langerhans cells, which are immature dendritic cells of the epidermis and mucosa, and its expression decreases during Langerhans cells maturation. Upon antigen binding CD207 localizes to the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed membranes, which leads to a nonclassical antigen-processing pathway.

flow cytometry: Recommended dilution: 0.5-4 μg/ml. Extracellular and intracellular staining.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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