Anti-CD206 / MMR Monoclonal Antibody (Clone:15-2)
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Format : | Purified |
Amount : | 0.1 mg |
Isotype : | Mouse IgG1 |
Purification : | Purified by protein-A affinity chromatography |
Storage condition : | Store at 2-8°C. Do not freeze. |
CD206 (macrophage mannose receptor, MMR), also known as mannose receptor C1 (MRC1), is a type I transmembrane glycoprotein serving as pattern recognition receptor for carbogydrate groups on the surface of bacteria, fungi and other pathogens. Expressed mainly on tissue macrophages and dendritic cells, CD206 mediates endocytosis of these pathogens and presentation of their antigens to the adaptive immune system. CD206 can also be detected in a soluble form in human plasma and is elevated in patients with acute sepsis.
Flow Cytometry Immunoprecipitation Western Blotting Immunohistochemistry (frozen sections) Immunocytochemistry Functional Application blocking
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
Subcellular location: | Endosome membrane, Cell membrane |
BioGrid: | 110500. 1 interactions. |
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