Anti-CD2 / LFA-2 Monoclonal Antibody (Clone:MEM-65)-Biotin Conjugated

Product code: 30-1832

Clone name : MEM-65
Clonality : Monoclonal
Application : FACS, IP
Reactivity : Human
Conjugate : Biotin

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0.1 mg
$433.00 

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Amount : 0.1 mg
Isotype : Mouse IgG1
Storage condition : Store at 2-8°C. Do not freeze.
Gene : CD2
Gene ID : 914
Uniprot ID : P06729
Alternative Name : T-cell surface antigen CD2, Erythrocyte receptor, T-cell surface antigen T11/Leu-5
Immunogen Information : Human peripheral T cells.
CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.
Subcellular location: Cell membrane
BioGrid: 107352. 16 interactions.
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