Anti-CD2 / LFA-2 Monoclonal Antibody (Clone:LT2)

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Product code: 30-1346

Clone name :	LT2
Clonality :	Monoclonal
Application :	FACS
Reactivity :	Human

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Download TDS MSDS

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Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

Format :	Purified
Amount :	0.1 mg
Isotype :	Mouse IgG2b
Purification :	Purified by protein-A affinity chromatography
Storage condition :	Store at 2-8°C. Do not freeze.


Gene :	CD2
Gene ID :	914
Uniprot ID :	P06729
Alternative Name :	T-cell surface antigen CD2, Erythrocyte receptor, T-cell surface antigen T11/Leu-5
Immunogen Information :	Normal human blood lymphocytes.

CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.