Anti-CD1a / HTA1 (Mature Langerhans Cells Marker) Monoclonal Antibody(Clone: C1A/3249)

Name: Anti-CD1a / HTA1 (Mature Langerhans Cells Marker) Monoclonal Antibody(Clone: C1A/3249)
Brand: Abeomics
SKU: 36-3453
Price: 520.0000 USD
Availability: InStock
Rating: 4.3 (10 reviews)

Fig. 1: SDS-PAGE Analysis Purified CD1a Mouse Monoclonal Antibody (C1A/3249). Confirmation of Purity and Integrity of Antibody.

Anti-CD1a / HTA1 (Mature Langerhans Cells Marker) Monoclonal Antibody(Clone: C1A/3249)

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Fig. 1: SDS-PAGE Analysis Purified CD1a Mouse Monoclonal Antibody (C1A/3249). Confirmation of Purity and Integrity of Antibody.

Fig. 2: Analysis of Protein Array containing more than 19,000 full-length human proteins using CD1a Mouse Monoclonal Antibody (C1A/3249). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Product code: 36-3453

Clone name :	C1A/3249
Clonality :	Monoclonal
Application :	ELISA
Reactivity :	Human

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Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

Amount :	100 µg
Isotype :	Mouse IgG2b, kappa
Content :	200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition :	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.


Gene :	CD1A
Gene ID :	909
Uniprot ID :	P06126
Alternative Name :	Cortical thymocyte antigen CD1A, Epidermal dendritic cell marker CD1a, FCB6, HTA1, T cell surface antigen T6 / Leu 6, T-Cell Surface Glycoprotein CD1A
Immunogen Information :	Recombinant fragment (around aa43-173) of human CD1A protein (exact sequence is proprietary)

At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta-2 microglobulin. Anti-CD1a labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibodies against TTF-1 and CD5, anti-CD1a is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic lymphocytes in both typical and atypical thymomas, but only focally in 1/6 of thymic carcinomas and not in lymphocytes in pulmonary neoplasms. Anti-CD1a is reported to be a new marker for perivascular epithelial cell tumor (PEComa).

ELISA (For coating, order Ab without BSA);

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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