Anti-CD18 / Integrin beta2 subunit Monoclonal Antibody (Clone:M18/2)
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| Format : | Purified |
| Amount : | 0.1 mg |
| Isotype : | Rat IgG2a |
| Purification : | Purified by protein-A affinity chromatography |
| Storage condition : | Store at 2-8°C. Do not freeze. |
CD18, integrin beta2 subunit, forms heterodimers with four types of CD11 molecule to constitute leukocyte (beta2) integrins: alphaLbeta2 (CD11a/CD18, LFA-1), alphaMbeta2 (CD11b/CD18, Mac-1, CR3), alphaXbeta2 (CD11c/CD18) and alphaDbeta2 (CD11d/CD18). In most cases, the response mediated by the integrin is a composite of the functions of its individual subunits. These integrins are essential for proper leukocyte migration, mediating intercellular contacts.
Flow Cytometry Recommended dilution: 1 µg/ml
Immunoprecipitation Western Blotting Immunohistochemistry Immunohistochemistry (frozen sections) Functional Application Blocking or stimulation
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cell membrane, Membrane raft |
| BioGrid: | 200828. 2 interactions. |
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