Anti-CD18 / Integrin beta2 subunit Monoclonal Antibody (Clone:M18/2)

Product code: 30-1434

Clone name : M18/2
Clonality : Monoclonal
Application : FACS, IP, WB, IHC, IHC-Fr, Functional Assay
Reactivity : Mouse

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0.1 mg
$345.00 

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Format : Purified
Amount : 0.1 mg
Isotype : Rat IgG2a
Purification : Purified by protein-A affinity chromatography
Storage condition : Store at 2-8°C. Do not freeze.
Gene : Itgb2
Gene ID : 16414
Uniprot ID : P11835
Alternative Name : Itgb2
Immunogen Information : Murine cytotoxic T cell glycoproteins
CD18, integrin beta2 subunit, forms heterodimers with four types of CD11 molecule to constitute leukocyte (beta2) integrins: alphaLbeta2 (CD11a/CD18, LFA-1), alphaMbeta2 (CD11b/CD18, Mac-1, CR3), alphaXbeta2 (CD11c/CD18) and alphaDbeta2 (CD11d/CD18). In most cases, the response mediated by the integrin is a composite of the functions of its individual subunits. These integrins are essential for proper leukocyte migration, mediating intercellular contacts.

Flow Cytometry Recommended dilution: 1 µg/ml
Immunoprecipitation Western Blotting Immunohistochemistry Immunohistochemistry (frozen sections) Functional Application Blocking or stimulation

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cell membrane, Membrane raft
BioGrid: 200828. 2 interactions.
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