Anti-CD178 / Fas-L Monoclonal Antibody (Clone:NOK-1)-Low Endotoxin

Product code: 30-1656

Clone name : NOK-1
Clonality : Monoclonal
Application : FACS, IP, WB, ICC, Functional Assay
Reactivity : Human

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0.1 mg
$389.00 

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Format : Low Endotoxin
Amount : 0.1 mg
Isotype : Mouse IgG1
Purification : Purified by protein-A affinity chromatography
Storage condition : Store at 2-8°C. Do not freeze.
Gene : FASLG
Gene ID : 356
Uniprot ID : P48023
Alternative Name : FASLG, APT1LG1, CD95L, FASL, TNFSF6
Immunogen Information : L5178Y mouse T lymphoma cells expressing recombinant human CD178
CD178 / Fas-L (Fas ligand, CD95L), a member of TNF family transmembrane glycoproteins, is responsible for induction of apoptosis in cells containing its receptor CD95 / Fas. The CD178-mediated apoptosis pathway has been implicated in peripheral tolerance, tissue pathology, and maintenance of the immune privileged sites. Defects in this interaction may be related to some cases of systemic lupus erythematosus (SLE). CD178 was also described as a co-stimulatory receptor for T-cell activation in mice in vivo.

Flow Cytometry Immunoprecipitation Western Blotting Immunocytochemistry Functional Application blocking

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Nucleus
Post transnational modification: Monoubiquitinated.
BioGrid: 106852. 83 interactions.
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