Anti-CD160 Monoclonal Antibody (Clone:BY55)-APC Conjugated

Product code: 30-1818

Clone name : BY55
Clonality : Monoclonal
Application : FACS
Reactivity : Human
Conjugate : APC

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100 tests
$499.00 

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Shipping Info:

For estimated delivery dates, please contact us at [email protected]


Amount : 100 tests
Isotype : Mouse IgM,kappa
Content : Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage condition : Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Gene : CD160
Gene ID : 11126
Uniprot ID : O95971
Alternative Name : CD160, BY55
Immunogen Information : Human NK cell line YT2C2

CD160 is a cell surface glycoprotein of immunoglobulin superfamily, which functions as a costimulatory receptor expressed mainly on cytotoxic cell populations and recognizing both classical and non-classical MHC class I molecules. It can form disulfide-linked multimers. Down-modulation of CD160 occurs as a consequence of its proteolytic cleavage and the released soluble form was found to impair the MHC-class I specific cytotoxicity of CD8+ T lymphocytes and NK cells. In contrast to GPI-anchored isoform with broader expression among CD160 positive cells, expression of the transmembrane isoform is restricted to NK cells and is activation-dependent.

Subcellular location: Cell membrane
Tissue Specificity: Expressed in spleen, peripheral blood, and small intestine. Expression is restricted to functional NK and T cytotoxic lymphocytes.
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