Anti-CD160 antibody(DMC270), IgG1 Chimeric mAb

Product code: 12-9213

Clone name : DMC270
Clonality : Monoclonal
Application : FACS
Reactivity : Human

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Size
Price
100 µg
$637.00 

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Amount : 100 µg
Purification : Purified from cell culture supernatant by affinity chromatography
Content :
Not Sterile
Storage condition : Store at -20°C for 12 months (Avoid repeated freezing and thawing)
Alternative Name : BY55, NK1, NK28

CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules.

FACS 1/100

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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