Anti-CD158d / KIR2DL4 Monoclonal Antibody (Clone:mAb#33)-PE Conjugated
Figure 1: Separation of cells stained using anti-human CD158d (mAb#33) PE antibody from cells stained using mouse IgG1 isotype control (MOPC-21) PE antibody in flow cytometry analysis (surface staining) of NKL cell suspension.
Roll over image to zoom in
Shipping Info:
For estimated delivery dates, please contact us at [email protected]
| Amount : | 100 tests |
| Isotype : | Mouse IgG1 |
| Storage condition : | Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. |
CD158d / KIR2DL4 is a KIR family member that shares structural features with both activating and inhibitory receptors and may mediate different functions under different circumstances. It contains cytoplasmic ITIM, suggesting inhibitory function, but also transmembrane domain similar to those of activating KIRs. It has been reported that CD158d serves as an inhibitory receptor for peripheral and uterine NK cells, but its ligation with soluble mAbs (unlike immobilized mAbs) results in activation of IFN-gamma secretion. CD158d also binds both membrane form and soluble form of its ligand HLA-G.
| Subcellular location: | Cell membrane |
| BioGrid: | 110006. 5 interactions. |
|
There are currently no product reviews
|
.png "ACE2/HEK293 Stable Cell Line")
