Anti-CD15 / Lewis x Blood Group antigen Monoclonal Antibody (Clone:MEM-158)-FITC Conjugated

Product code: 30-1943

Clone name : MEM-158
Clonality : Monoclonal
Application : FACS, IP
Reactivity : Human
Conjugate : FITC

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100 tests
$433.00 

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Amount : 100 tests
Isotype : Mouse IgM
Storage condition : Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Immunogen Information : Human granulocytes
CD15 (Lewis X, Le(x); stage specific embryonic antigen-1, SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin´s disease.
Subcellular location: Membrane
BioGrid: 129146. 1 interactions.
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