Anti-CD147 / Basigin / Neurothelin Monoclonal Antibody (Clone:MEM-M6/1)-PE Conjugated
Figure 1: Surface staining of human peripheral blood with anti-human CD147 (MEM-M6/1) PE.
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| Amount : | 100 tests |
| Isotype : | Mouse IgG1 |
| Storage condition : | Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. |
| Gene : | BSG |
| Gene ID : | 682 |
| Uniprot ID : | P35613 |
| Alternative Name : | BSG, UNQ6505/PRO21383 |
| Immunogen Information : | Protein A-CR purified soluble recombinant form of CD147, CD147Rg, which consists of the cDNA coding for the hinge region, CH2-and CH3 domain of human IgG1 (CD147Rg is secreted by transfectants as a dimer). |
CD147 (basigin, neurothelin, OX-47, 5A11, CE9, M6) also known as EMMPRIN (extracellular matrix metalloproteinase inducer) or TCSF (tumour cell-derived collagenase-stimulatory factor) is an ubiquitously expressed cell surface protein with multiple glycosylated forms. The highest level of CD147 expression is on metabolically active cells, such as lymphoblasts, inflammatory cells, brown adipocytes and malignant tumour cells. CD147 has multiple functions, including facilitating of cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulation of integrin functions, it plays roles in cell development and activation, fetal development or retinal function.
| Subcellular location: | Cell membrane, Melanosome |
| Post transnational modification: | N-glycosylated. |
| Tissue Specificity: | Present only in vascular endothelium in non-neoplastic regions of the brain, whereas it is present in tumor cells but not in proliferating blood vessels in malignant gliomas. |
| BioGrid: | 107147. 159 interactions. |
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