Anti-CD140b / PDGF-RB Monoclonal Antibody (Clone:18A2)-PE Conjugated
Roll over image to zoom in
Shipping Info:
For estimated delivery dates, please contact us at [email protected]
| Amount : | 100 tests |
| Isotype : | Mouse IgG1 |
| Storage condition : | Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. |
CD140b / PDGF-RB (platelet-derived growth factor receptor beta) is a cell surface receptor for members of platelet-derived growth factor family, whose intracellular part contains a tyrosine kinase domain. CD140b forms homodimers, or heterodimerizes with CD140a / PDGF-RA. Whereas CD140a can have both pro-proliferative or anti-proliferative effects, the CD140b induces in various cell types their proliferation and migration. CD140b has also developmental roles in the cardiovascular system and is preferentially expressed on some tumours such as medulloblastoma.
| Subcellular location: | Cell membrane, Cytoplasmic vesicle, Lysosome lumen |
| Post transnational modification: | Ubiquitinated. After autophosphorylation, the receptor is polyubiquitinated, leading to its degradation. |
| BioGrid: | 111185. 78 interactions. |
|
There are currently no product reviews
|
.png "ACE2/HEK293 Stable Cell Line")
