Anti-CD132 Monoclonal Antibody (Clone: TUGh4) Purified
Figure 1: Flow cytometry surface staining pattern of human peripheral blood stained using anti-human CD132 (TUGh4) purified antibody GAM APC.
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| Format : | Purified |
| Amount : | 0.1 mg |
| Isotype : | Rat IgG2b |
| Purification : | Purified from hybridoma culture supernatant by protein-G affinity chromatography. |
| Storage condition : | Store at 2-8°C. Do not freeze. |
CD132 / common gamma chain is an essential component of receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21, and it is critical for development of the immune system. Its mutation causes X-linked severe combined immunodeficiency disease (XSCID). CD132 is expressed on lymphocytes, NK cells, monocytes, and granulocytes. Through its cytoplasmic part which containsfour tyrosines and an SH2 domain, CD132 transcuces signal to downstream JAK/STAT pathway.
| Subcellular location: | Membrane |
| BioGrid: | 109776. 22 interactions. |
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