Anti-CD129 / IL-9R alpha Monoclonal Antibody (Clone:AH9R7)
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| Format : | Purified |
| Amount : | 0.1 mg |
| Isotype : | Mouse IgG2b |
| Purification : | Purified by protein-A affinity chromatography |
| Storage condition : | Store at 2-8°C. Do not freeze. |
CD129 serves as the high affinity alpha subunit of IL-9 receptor. It associates with CD132, the common gamma chain shared by receptors of many different cytokines. CD129 is expressed at low levels by T and B cells, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons. Its signaling (through JAK/STAT pathways) results in proliferative and anti-apoptotic response, which is critical e.g. for intrathymic T cell development and survival of various cell types. The gene for CD129 is located at the pseudoautosomal regions of X and Y chromosomes and it may be related with the development of asthma.
Flow Cytometry Application note:it is recommended to use bright fluorochromes or signal multiplying detection
ELISA Functional Application blocking
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cell membrane, Secreted |
| BioGrid: | 109795. 23 interactions. |
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