Anti-CD122 Monoclonal Antibody (Clone:TU27)

Product code: 30-1104

Clone name : TU27
Clonality : Monoclonal
Application : FACS, IP, Functional Assay
Reactivity : Human

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0.1 mg
$389.00 

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Format : Purified
Amount : 0.1 mg
Isotype : Mouse IgG1
Purification : Purified by protein-A affinity chromatography
Storage condition : Store at 2-8°C. Do not freeze.
Gene : IL2RB
Gene ID : 3560
Uniprot ID : P14784
Alternative Name : IL2RB, IL15RB
Immunogen Information : TL-Mor cell line
CD122 (IL-2/IL-15R beta) constitutes together with CD132 (common gamma chain) and with CD25 (IL-2/IL15R alpha) the intermediate (CD122+CD132) and the high affinity (CD122+CD132+CD25) IL-2 and IL-15 receptor complex. CD122 is expressed on NK cells and lymphocytes, but at low level, unless the cell is activated. The cytoplasmic part of CD122 binds to Src-family and Jak-family kinases. The biological effect of CD122 ligation depends on whether IL-2 or IL-15 is bound to the receptor complex.

Flow Cytometry Immunoprecipitation Functional Application blocking

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Membrane
BioGrid: 109775. 18 interactions.
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