Anti-CD11c Monoclonal Antibody (Clone:BU15)-FITC Conjugated

Product code: 30-2027

Clone name : BU15
Clonality : Monoclonal
Application : FACS, IP, IHC-Fr
Reactivity : Human, Monkey
Conjugate : FITC

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100 tests
$433.00 

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Amount : 100 tests
Isotype : Mouse IgG1
Storage condition : Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Gene : ITGAX
Gene ID : 3687
Uniprot ID : P20702
Alternative Name : ITGAX, CD11C
Immunogen Information : Dendritic cells of synovial fluid
CD11c (p150, alphaX integrin subunit) forms complex with CD18 (beta2 integrin subunit) and is expressed mainly on tissue macrophages and dendritic cells. CD11c binds to complement fragment iC3b, fibrinogen, VCAM-1 and ICAM-2 or e.g. CD90. Like other beta2 integrins, CD11c/CD18 plays roles in cell migration and phagocytosis. Moreover, interaction of CD11c/CD18 with plasminogen regulates plasmin activities, and interaction with heparin counteracts binding of iC3b.
Subcellular location: Membrane
Tissue Specificity: Predominantly expressed in monocytes and granulocytes.
BioGrid: 109893. 1 interactions.
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