Anti-CD111 / Nectin-1 Monoclonal Antibody (Clone:R1.302)

Product code: 30-1563

Clone name : R1.302
Clonality : Monoclonal
Application : FACS, IP, WB, IHC, ICC
Reactivity : Human

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0.1 mg
$389.00 

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Format : Purified
Amount : 0.1 mg
Isotype : Mouse IgG1
Purification : Purified by protein-A affinity chromatography
Storage condition : Store at 2-8°C. Do not freeze.
Gene : NECTIN1
Gene ID : 5818
Uniprot ID : Q15223
Alternative Name : NECTIN1, HVEC, PRR1, PVRL1
Immunogen Information : NIH/3T3 cells transfected with human CD111
CD111, also known as nectin-1, is a calcium-independent cell-cell adhesion transmembrane glycoprotein involved in organization of adherens junctions and tight junctions in epithelial and endothelial cells. It also serves as a target molecule for entry of herpes simplex virus (HSV-1, HSV-2) and pseudorabies virus (PRV) into epithelial and neuronal cells. CD111 is connected with actin cytoskeleton through afadin. Mutations in the gene for CD111 cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.
Subcellular location: Secreted
BioGrid: 111776. 10 interactions.
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