Biotin Conjugated, Anti-CD105 / Endoglin Monoclonal Antibody (Clone:MEM-229)
Figure 1: Flow cytometry analysis (surface staining) of CD105 on HUVEC and HEK-293 cells with anti-CD105 (30-1887) biotin.
Roll over image to zoom in
Shipping Info:
For estimated delivery dates, please contact us at [email protected]
| Amount : | 0.1 mg |
| Isotype : | Mouse IgG2a |
| Content : | 1mg/ml, antibody suspended in phosphate buffered saline (PBS) solution containing 0.2% BSA and 15 mM sodium azide |
| Storage condition : | Store at 2-8°C. Do not freeze. |
CD105 (Endoglin) is a homodimeric transmembrane glycoprotein serving in presence of TGFbetaR-2 as a receptor for TGFbeta-1 and TGFbeta-3. CD105 is highly expressed on endothelial cells and promotes angiogenesis during wound healing, infarcts and in a wide range of tumours and its gene expression is stimulated by hypoxia. CD105 prevents apoptosis in hypoxic endothelial cells and also antagonises the inhibitory effects of TGFbeta-1 on vascular endothelial cell growth and migration. Normal cellular levels of CD105 are required for formation of new blood vessels.
Flow cytometry: Recommended dilution: 8 μg/ml; positive control: Kg1 human acute myelogenous leukemia cell line.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cell membrane |
| Tissue Specificity: | Detected on umbilical veil endothelial cells (PubMed:10625079). Detected in placenta (at protein level) (PubMed:1692830). Detected on endothelial cells (PubMed:1692830). |
| BioGrid: | 108337. 12 interactions. |
|
There are currently no product reviews
|
.png "ACE2/HEK293 Stable Cell Line")
