Anti-CD102 / ICAM-2 Monoclonal Antibody (Clone:CBR-IC2/2)
Figure 1:Flow cytometry analysis of human peripheral blood with anti-human CD102 .
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| Format : | Purified |
| Amount : | 0.1 mg |
| Isotype : | Mouse IgG2a |
| Purification : | Purified by protein-A affinity chromatography |
| Content : | 1mg/ml, Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Storage condition : | Store at 2-8°C. Do not freeze. |
CD102 / ICAM-2 (intracellular cell adhesion molecule-2), a counter receptor of LFA-1 (CD11a/CD18), is a transmembrane glycoprotein with two extracellular IgC-like domains and intracellular C-terminal tail. It is involved in lymphocyte recirculation and homing to the sites of inflammation. Through interaction with integrins it provides to the immune cells costimulatory signals. Expression of CD102 on blood cells (lymphocytes, monocytes, thrombocytes) is lower than on endothelium and follicular dendritic cells. CD102 levels are upregulated in lymph nodes with malignant infiltration.
Flow cytometry: Recommended dilution: 2-4 μg/ml.
Flow cytometry: Recommended dilution: 2-4 μg/ml.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Membrane, Cell projection |
| BioGrid: | 109611. 18 interactions. |
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