Anti-CD10 / CALLA Monoclonal Antibody (Clone:LT10)

Product code: 30-1284

Clone name : LT10
Clonality : Monoclonal
Application : FACS
Reactivity : Human

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0.1 mg
$389.00 

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Format : Purified
Amount : 0.1 mg
Isotype : Mouse IgG1
Purification : Purified by precipitation and chromatography
Storage condition : Store at 2-8°C. Do not freeze.
Gene : MME
Gene ID : 4311
Uniprot ID : P08473
Alternative Name : MME, EPN
Immunogen Information : mouse NALM-6 leukemia pre-B cell line (tissue/cell preparation)

CD10 (neutral endopeptidase - NEP, common acute lymphocytic leukemia antigen - CALLA, membrane metallo-endopeptidase - MME, enkefalinase) is a 100-kDa cell surface zinc metalloprotease cleaving peptide bonds on the N-terminus of hydrophobic amino acids and inactivating multiple physiologically active peptids. CD10 is expressed on various normal cell types, including lymphoid precursor cells, germinal center B lymhocytes, and some epithelial cells, and its expression level serves as a marker for diagnostics of many carcinomas. CD10 is also a differentiation antigen for early B-lymphoid progenitors in the B-cell differentiation pathway and has a key role in regulation of growth, differentiation and signal transduction of many cellular systems.

Subcellular location: Cell membrane
Post transnational modification: Glycosylation at Asn-628 is necessary both for surface expression and neutral endopeptidase activity.
BioGrid: 110455. 102 interactions.
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