Anti-Cathepsin K (Marker of Tumor Invasiveness) Monoclonal Antibody(Clone: CTSK/2793)

Name: Anti-Cathepsin K (Marker of Tumor Invasiveness) Monoclonal Antibody(Clone: CTSK/2793)
Brand: Abeomics
SKU: 36-2150
Price: 520.0000 USD
Availability: InStock
Rating: 4.2 (10 reviews)

Fig. 1: Formalin-fixed, paraffin-embedded human Liver stained with Cathepsin K Mouse Monoclonal Antibody (CTSK/2793).

Anti-Cathepsin K (Marker of Tumor Invasiveness) Monoclonal Antibody(Clone: CTSK/2793)

Roll over image to zoom in

Fig. 1: Formalin-fixed, paraffin-embedded human Liver stained with Cathepsin K Mouse Monoclonal Antibody (CTSK/2793).

Fig. 2: Formalin-fixed, paraffin-embedded human Hepatocellular Carcinoma stained with Cathepsin K Mouse Monoclonal Antibody (CTSK/2793).

Fig. 3: SDS-PAGE Analysis Purified Cathepsin K Mouse Monoclonal Antibody (CTSK/2793). Confirmation of Purity and Integrity of Antibody

Fig. 4: Analysis of Protein Array containing more than 19,000 full-length human proteins using Cathepsin K Mouse Monoclonal Antibody (CTSK/2793) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Product code: 36-2150

Clone name :	CTSK/2793
Clonality :	Monoclonal
Application :	IHC
Reactivity :	Human

Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

Write a review for this product on BioCompare

Get $20 gift card from Amazon

Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

Amount :	100 µg
Isotype :	Mouse IgG1, kappa
Content :	200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition :	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.


Gene :	CTSK
Gene ID :	1513
Uniprot ID :	P43235
Alternative Name :	Cathepsin K; Cathepsin O; Cathepsin O1; Cathepsin O2; Cathepsin X; CTS02; Ctsk; CTSO1; CTSO2; PKND; PYCD
Immunogen Information :	Recombinant fragment of human Cathepsin K protein (around aa 163-274) (exact sequence is proprietary)

The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature.

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT) ,(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes);

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

There are currently no product reviews

Write a review on this product!