Anti-Cathepsin D (Tumor Marker) Monoclonal Antibody(Clone: CTSD/3276)

Name: Anti-Cathepsin D (Tumor Marker) Monoclonal Antibody(Clone: CTSD/3276)
Brand: Abeomics
SKU: 36-2147
Price: 520.0000 USD
Availability: InStock
Rating: 4.6 (10 reviews)

Fig. 1: Formalin-fixed, paraffin-embedded human Liver stained with Cathepsin D Mouse Monoclonal Antibody (CTSD/3276).

Anti-Cathepsin D (Tumor Marker) Monoclonal Antibody(Clone: CTSD/3276)

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Fig. 1: Formalin-fixed, paraffin-embedded human Liver stained with Cathepsin D Mouse Monoclonal Antibody (CTSD/3276).

Fig. 2: SDS-PAGE Analysis Purified Cathepsin D Mouse Monoclonal Antibody (CTSD/3276). Confirmation of Integrity and Purity of Antibody

Fig. 3: Analysis of Protein Array containing more than 19,000 full-length human proteins using Cathepsin D Mouse Monoclonal Antibody (CTSD/3276) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Product code: 36-2147

Clone name :	CTSD/3276
Clonality :	Monoclonal
Application :	IF, WB, IHC
Reactivity :	Human

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Download TDS MSDS

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Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

Amount :	100 µg
Isotype :	Mouse IgG2b, kappa
Content :	200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition :	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.


Gene :	CTSD
Gene ID :	1509
Uniprot ID :	P07339
Alternative Name :	CatD; Cathepsin D; Ceroid lipofuscinosis neuronal 10; CLN10; CPSD; Epididymis secretory sperm binding protein Li 130P; Lysosomal aspartyl peptidase; Lysosomal aspartyl protease
Immunogen Information :	Recombinant fragment of human Cathepsin D protein (around aa 104-250) (exact sequence is proprietary)

Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 43kDa preprocathepsin D that is cleaved and glycosylated to form a 46kDa procathepsin D and then further cleaved to produce 28kDa and 15kDa subunits (heavy and light chains, respectively). Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.

Immunofluorescence (1-2ug/ml); Western Blot (1-2ug/ml); Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes);

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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