Anti-Cathepsin D (Tumor Marker) Monoclonal Antibody(Clone: CTSD/2781)
Fig. 1: Formalin-fixed, paraffin-embedded human Renal Cell Carcinoma stained with Cathepsin D Mouse Monoclonal Antibody (CTSD/2781).
Roll over image to zoom in
Shipping Info:
For estimated delivery dates, please contact us at [email protected]
| Amount : | 100 µg |
| Isotype : | Mouse IgG1, kappa |
| Content : | 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Storage condition : | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. |
| Gene : | CTSD |
| Gene ID : | 1509 |
| Uniprot ID : | P07339 |
| Alternative Name : | CatD; Cathepsin D; Ceroid lipofuscinosis neuronal 10; CLN10; CPSD; Epididymis secretory sperm binding protein Li 130P; Lysosomal aspartyl peptidase; Lysosomal aspartyl protease |
| Immunogen Information : | Recombinant fragment of human Cathepsin D protein (around aa 104-250) (exact sequence is proprietary) |
Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 43kDa preprocathepsin D that is cleaved and glycosylated to form a 46kDa procathepsin D and then further cleaved to produce 28kDa and 15kDa subunits (heavy and light chains, respectively). Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.
Western Blot (1-2ug/ml); Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes);
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
|
There are currently no product reviews
|
.png "ACE2/HEK293 Stable Cell Line")
