Anti-Canine PD-1 antibody(4E1), Rabbit mAb
Figure 1. Elisa plates were pre-coated with His Tagged Canine PD-1 protein (0.1μg/per well). 0.2μg of Canine PDL1, hFc Tagged protein and serial dilutions of anti-Canine PD-1 monoclonal antibody were added, and Goat anti Human IgG(Horseradish Peroxidase Conjugate) was used as the secondary antibody. From the above data, the biosimilar(Red) and clone 4E1(Green) have good competitive activity, and Rabbit IgG(Blue) was used as the Isotype Control.
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| Amount : | 100 μg |
| Isotype : | Rabbit IgG |
| Purification : | Purified from cell culture supernatant by affinity chromatography |
| Content : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage condition : | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Gene : | Canine PD-1 |
| Uniprot ID : | NP_001301026.1 |
| Alternative Name : | PD1; PDCD1; CD279; SLEB2; hPD-1; hPD-l; hSLE1 |
Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020]
ELISA 1/5000-10000
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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