Anti-BSEP Monoclonal Antibody (Clone:IHC518)-Ready to Use
Figure 1: Immunohistochemical analysis of BSEP (Clone: IHC518) on Liver
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Shipping Info:
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| Amount : | 7 ml |
| Isotype : | Mouse IgG1 |
| Purification : | Protein A/G Chromatography |
| Content : | Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide |
| Storage condition : | Store at 2°C - 8°C. Do not freeze. |
"Bile Salt Export Pump (BSEP) is a member of the ATP-binding cassette (ABC) transporters, which mediates the transport of bile acid, taurocholate and other cholate conjugates across the hepatocyte canalicular membrane into the canaliculus. BSEP is associated with progressive familial intrahepatic cholestasis type 2 (PFIC2) and benign recurrent intrahepatic cholestasis type 2 (BRIC2). PFIC2 caused by mutations in the BSEP gene increases the risk of hepatocellular carcinoma in early life."
This product is available in ready to use format, hence no dilution is required.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Membrane |
| Tissue Specificity: | Expressed predominantly, if not exclusively in the liver, where it was further localized to the canalicular microvilli and to subcanalicular vesicles of the hepatocytes by in situ. |
| BioGrid: | 114199. 5 interactions. |
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