Anti-Blood Group ABH Monoclonal Antibody (Clone: HE-10) purified
Figure 1: Flow cytometry surface staining pattern of human peripheral whole blood from group A donor stained using anti-blood group ABH (HE-10) purified antibody (concentration in sample 4 μg/ml, GAM APC).
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Format : | Purified |
Amount : | 0.1 mg |
Isotype : | Mouse IgM |
Purification : | Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods). |
Content : | 1mg/ml, Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide |
Storage condition : | Store at 2-8°C. Do not freeze. |
Immunogen Information : | Mixture of erythrocytes of group A1 and glycoprotein fraction isolated from saliva of secretors with blood group A. |
The mouse monoclonal antibody HE-10 agglutinates erythrocytes of group A, and is excellent as a tumour marker in patients of blood group B and 0. It does not agglutinate erythrocytes of group B and 0. Study with specific oligosaccharides showed that the antibody HE-10 reacts with A and H antigens with chain types 3 and 4 and it does not react with A disaccharide, A trisaccharide, A type 1, A type 2, ALeb. The antibody HE-10 does not react with normal tissue sections of donors with blood group B and 0 but it reacts specifically with malignant tissues.
Flow cytometry: Recommended dilution: 1-4 µg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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