Anti-BAFF-R antibody(DM127), Rabbit mAb

Product code: 12-9301

Clone name : DM127
Clonality : Monoclonal
Application : FACS
Reactivity : Human

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Size
Price
100 µg
$637.00 

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For estimated delivery dates, please contact us at [email protected]


Amount : 100 µg
Purification : Purified from cell culture supernatant by affinity chromatography
Content :
Not Sterile
Storage condition : Store at -20°C for 12 months (Avoid repeated freezing and thawing)
Alternative Name : BAFFR,TNFRSF13C,BAFF-R,BROMIX,CD268,CVID4,prolixin

B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell surviva

FACS  1/100

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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