Anti-B7-H3 antibody(DM53), Rabbit mAb

Product code: 12-9043

Clone name : DM53
Clonality : Monoclonal
Application : ELISA, FACS
Reactivity : Human

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100 µg
$637.00 

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Amount : 100 µg
Isotype : Rabbit IgG
Purification : Purified from cell culture supernatant by affinity chromatography
Content : Preservative: 0.1% Procline 300
Constituents: 50% Glycerol; PBS,pH 7.4; 0.1% BSA
Not Sterile
Storage condition : Store at -20°C for 12 months (Avoid repeated freezing and thawing)
Alternative Name : B7-H3, CD276, B7 homolog 3, B7H3
Immunogen Information : Recombinant human  B7H3(Leu29-Pro245) produced by using human HEK293 cells

The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Recommended Dilutions ELISA 1/5000-10000;FACS  1/100

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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