Anti-Aldo-keto Reductase Family 1 Member C2 / DD2 Monoclonal Antibody(Clone: CPTC-AKR1C2-1)

Name: Anti-Aldo-keto Reductase Family 1 Member C2 / DD2 Monoclonal Antibody(Clone: CPTC-AKR1C2-1)
Brand: Abeomics
SKU: 36-2161
Price: 520.0000 USD
Availability: InStock
Rating: 4.4 (10 reviews)

Fig. 1: Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with AKR1C2 Mouse Monoclonal Antibody (CPTC-AKR1C2-1).

Anti-Aldo-keto Reductase Family 1 Member C2 / DD2 Monoclonal Antibody(Clone: CPTC-AKR1C2-1)

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Fig. 1: Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with AKR1C2 Mouse Monoclonal Antibody (CPTC-AKR1C2-1).

Fig. 2: Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with AKR1C2 Mouse Monoclonal Antibody (CPTC-AKR1C2-1).

Fig. 3: Western Blot Analysis of Human HeLa, K-562 and A431 cell lysates using AKR1C2 Mouse Monoclonal Antibody (CPTC-AKR1C2-1).

Fig. 4: SDS-PAGE Analysis Purified AKR1C2 Mouse Monoclonal Antibody (CPTC-AKR1C2-1). Confirmation of Purity and Integrity of Antibody.

Fig. 5: Analysis of Protein Array containing more than 19,000 full-length human proteins using Aldo-keto Reductase Family 1 Member C2 / DD2 Mouse Monoclonal Antibody (CPTC- AKR1C2-1). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Product code: 36-2161

Clone name :	CPTC-AKR1C2-1
Clonality :	Monoclonal
Application :	WB, IHC
Reactivity :	Human

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Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

Amount :	100 µg
Isotype :	Mouse IgG2a, kappa
Content :	200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition :	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.


Gene :	AKR1C2
Gene ID :	1646
Uniprot ID :	P52895
Alternative Name :	AKR1C2, 3-alpha-HSD3, AKR1C-pseudo protein, BABP, Dihydrodiol dehydrogenase 2, DD-2, MCDR2, HAKRD, DD, DDH2, HBAB, Pseudo-chlordecone reductase, SRXY8
Immunogen Information :	Recombinant human full-length AKR1C2 protein

DDH2 / AKR1C2 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone.

Western Blot (1-2ug/ml); Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes);

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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