Anti-AGR3 Monoclonal Antibody (Clone:AGR3.2)(Discontinued)

Product code: 30-1392

Clone name : AGR3.2
Clonality : Monoclonal
Application : WB, IHC-Fr, ICC
Reactivity : Human

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Format : Purified
Amount : 0.1 mg
Isotype : Mouse IgG1
Purification : Purified by protein-A affinity chromatography
Storage condition : Store at 2-8°C. Do not freeze.
Gene : AGR3
Gene ID : 155465
Uniprot ID : Q8TD06
Alternative Name : AGR3, BCMP11, PDIA18, UNQ642/PRO1272
Immunogen Information : Purified human AGR3 protein
AGR3 (Anterior Gradient 3) protein, also known as AG3 (hAG-3, HAG3 in human), or BCMP11, is a secreted cytoplasmic protein which is involved in metastasis induction and p53 tumour supressor inhibition. It may serve as molecular marker and potential therapeutic target for hormone-responsive breast tumours. Its Xenopus homolog is associated with anteroposterior fate determination during early development.

Western Blotting Recommended dilution: 1 µg/ml
Positive control: T47D breast cancer cell line
Negative control: H1299 lung carcinoma cell line

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Endoplasmic reticulum
Tissue Specificity: Expressed in the lung, in the ciliated cells of the airway epithelium (PubMed:25751668). Expression increased with differentiation of airway epithelial cells (PubMed:25751668). Not detected in the mucous cells (PubMed:25751668). Expressed in ciliated cells in the oviduct (PubMed:26170690). Also detected in stomach, colon, prostate and liver (PubMed:25751668). Expressed in breast, ovary, prostate and liver cancer (PubMed:26170690). Expression is associated with the level of differentiation of breast cancer (at protein level) (PubMed:26170690).
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