Animal-Free Recombinant Murine VEGF165(Discontinued)

Product code: 32-20249

Reactivity : Mouse

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Amount : 10 µg
Purification : Purity: >= 98% by SDS-PAGE gel and HPLC analyses.
AA sequence : MAPTTEGEQK SHEVIKFMDV YQRSYCRPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCAGC CNDEALECVP TSESNITMQI MRIKPHQSQH IGEMSFLQHS RCECRPKKDR TKPEKHCEPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR
Alternative Name : Vascular Endothelial Growth Factor165, Folliculostellate cell-derived growth factor, Glioma-derived endothelial cell mitogen, VEGF-A
Source:E.coli
VEGF is a potent growth and angiogenic cytokine.  It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability.  Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis.  Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes.  VEGF signals through three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product.  Recombinant Murine VEGF165 is a 39.0 kDa, disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.

Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 1.0-5.0 ng/ml.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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