Animal-Free Recombinant Murine TPO(Discontinued)

Product code: 32-20401

Reactivity : Human, Mouse

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For estimated delivery dates, please contact us at [email protected]


Amount : 10 µg
Purification : Purity:>= 98% by SDS-PAGE gel and HPLC analyses.
Content : This recombinant protein is supplied in lyophilized form.  
AA sequence : SPVAPACDPR LLNKLLRDSH LLHSRLSQCP DVDPLSIPVL LPAVDFSLGE WKTQTEQSKA QDILGAVSLL LEGVMAARGQ LEPSCLSSLL GQLSGQVRLL LGALQGLLGT QLPLQGRTTA HKDPNALFLS LQQLLRGKVR FLLLVEGPTL CVRRTLPTTA VPSSTSQLLT LNKF
Alternative Name : Thrombopoietin, Megakaryocyte colony-stimulating factor, c-MPL Ligand, MGDF
Source:E.coli
TPO is a lineage-specific growth factor produced in the liver, kidney and skeletal muscle. It stimulates the proliferation and maturation of megakaryocytes, and promotes increased circulating levels of platelets in vivo. TPO signals through the c-mpl receptor, and acts as an important regulator of circulating platelets. Human and murine TPO exhibit cross-species reactivity. Recombinant Murine TPO is a fully biologically active 174 amino acid polypeptide (18.7 kDa), which contains the erythropoietin-like domain of the full length TPO protein.

The ED50 as determined by the dose-dependent stimulation of the proliferation of human MO7e cells was found to be <=1.0 ng/ml, corresponding to a specific activity of>= 1 x 106 units/mg.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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