Animal-Free Recombinant Murine IL-6(Discontinued)

Product code: 32-20348

Reactivity : Monkey, Mouse

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For estimated delivery dates, please contact us at [email protected]


Amount : 10 µg
Purification : Purity: >= 98% by SDS-PAGE gel and HPLC analyses.
Content : This recombinant protein is supplied in lyophilized form.  
AA sequence : MFPTSQVRRG DFTEDTTPNR PVYTTSQVGG LITHVLWEIV EMRKELCNGN SDCMNNDDAL AENNLKLPEI QRNDGCYQTG YNQEICLLKI SSGLLEYHSY LEYMKNNLKD NKKDKARVLQ RDTETLIHIF NQEVKDLHKI VLPTPISNAL LTDKLESQKE WLRTKTIQFI LKSLEEFLKV TLRSTRQT
Alternative Name : 26 kDa protein, IFN-Beta2, B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, MGI-2
Source:E.coli
IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses.  Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions.  It stimulates B cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism.  IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6RAlpha and gp130.  Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells.  Recombinant Murine IL-6 is a 21.7 kDa protein containing 188 amino acid residues.

Determined by its ability to stimulate the proliferation of mouse 7TD1 cells. The expected ED50is <= 0.02 ng/ml, corresponding to a specific activity of >= 5 x 107 units/mg.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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