Animal-Free Recombinant Human VEGF165(Discontinued)

Product code: 32-20247

Reactivity : Cow, Guinea Pig, Human, Mouse, Pig, Rabbit, Rat, Sheep

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Amount : 10 µg
Purification : Purity: >= 98% by SDS-PAGE gel and HPLC analyses.
AA sequence : APMAEGGGQN HHEVVKFMDV YQRSYCHPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCGGC CNDEGLECVP TEESNITMQI MRIKPHQGQH IGEMSFLQHN KCECRPKKDR ARQENPCGPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR
Alternative Name : Vascular Endothelial Growth Factor, Folliculostellate cell-derived growth factor, Glioma-derived endothelial cell mitogen, VEGF-A
Source:E.coli
VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant Human VEGF165 is a 38.2 kDa, disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.

Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 1.0-8.0 ng/ml. 

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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