Animal-Free Recombinant Human SDF-1Alpha (CXCL12)(Discontinued)
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| Amount : | 10 µg |
| Purification : | Purity:>= 98% by SDS-PAGE gel and HPLC analyses. |
| Content : | This recombinant protein is supplied in lyophilized form. |
| AA sequence : | KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNK |
| Alternative Name : | Stromal-Cell Derived Factor-1, CXCL12, PBSF |
Source:E.coliSDF-1Alpha and Beta are stromal-derived, CXC chemokines that signal through the CXCR4 receptor. SDF-1Alpha and Beta chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV-suppressive activity in cells expressing the CXCR4 receptor. Human and murine SDF-1 proteins act across species. SDF-1Alpha and Beta contain the four highly conserved cysteine residues present in CXC chemokines. The mature SDF-1Alpha protein is the result of alternative splicing of the SDF-1 gene and contains 68 amino acid residues. Recombinant Human SDF-1Alpha is an 8.0 kDa protein containing 68 amino acid residues.
Determined by its ability to chemoattract human peripheral T cells activated with PHA and IL-2 using a concentation of 20-80 ng/ml.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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