Animal-Free Recombinant Human FGF-21(Discontinued)
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| Amount : | 25 µg |
| Purification : | Purity: >= 95% by SDS-PAGE gel and HPLC analyses. |
| Content : | This recombinant protein is supplied in lyophilized form. |
| AA sequence : | MHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY AS |
| Alternative Name : | Fibroblast Growth Factor-21, FGFL |
Source:E.coliFGF-21 is a secreted growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-21, in the presence of Beta -Klotho as a protein cofactor, signals through FGFR 1c and 4 receptors, and stimulates insulin-independent glucose uptake by adipocytes. Recombinant Human FGF-21 is a 19.5 kDa protein containing 182 amino acid residues.
Determined by its ability to stimulate the proliferation of murine NIH-3T3 cells. The expected ED50for this effect is 0.3-0.6 µg/ml, in the presence of murine Klotho.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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