Alexa Fluor 488 Conjugated Anti-Human CD303 Mab (Clone:15E3)

Product code: 30-2877AF488

Clone name : 15E3
Clonality : Monoclonal
Application : IHC-Fr, ICC, FACS
Reactivity : Human

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100 tests
$499.00 

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Amount : 100 tests
Isotype : Mouse IgG1 kappa
Purification : Purified antibody is conjugated with Alexa Fluor 488 NHS ester under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Content : Formulation: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage condition : Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Gene : CD303
Gene ID : 170482
Uniprot ID : Q8WTT0
Alternative Name : BDCA2; CLEC4C; DLEC; HECL; CLECSF7;CLECSF11; PRO34150
Immunogen Information : CD303 ectodomain fused with human IgG Fc domain
CD303 is an approximately 38 kDa type II transmembrane glycoprotein with an extracellular C-type lectin domain. It is a specific marker of plasmacytoid dendritic cells, and plays roles in capturing of pathogen-related oligosaccharide-containing antigens by them, and in their presentation to T cells. CD303 also mediates a potent inhibition of interferon alpha/beta production in plasmacytoid dendritic cells, thus it represents a potential target for lupus erythematosus therapy.
Specificity: The mouse monoclonal antibody 15E3 recognizes an extracellular epitope of human CD303, a transmembrane glycoprotein expressed on plasmacytoid dendritic cells.

Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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