Polyclonal Antibody to p65
Fig-1: Western blot analysis of P65. Anti-P65 antibody (11-6002) was used at 2 µg/ml on Daudi lysate.
Roll over image to zoom in
Shipping Info:
Order now and get it on Wednesday July 03, 2024
Same day delivery FREE on San Diego area orders placed by 1.00 PM
| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Rabbit IgG |
| Purification : | Protein A Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles. |
P65 is a subunit of the NF-KappaB, a second messenger, which activates the transcription of a number of genes in multiple tissues. It is a ubiquitously expressed protein that can bind to the kB site alone. In addition, p65 is shown to be the subunit responsible for providing transcriptional activity of the NF-kB (p65-p50) heterodimeric complex. The inhibitory effect of I-KappaB upon NF-KappaB in the cytoplasm is exerted primarily through the interaction with P65. It shows a weak DNA binding site, which could contribute directly to DNA binding in the NF-KappaB complex.
Western blot analysis: 2-4 µg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Nucleus, Cytoplasm |
| Post transnational modification: | Proteolytically cleaved within a conserved N-terminus region required for base-specific contact with DNA in a CPEN1-mediated manner, and hence inhibits NF-kappa-B transcriptional activity (PubMed:18212740). |
| BioGrid: | 111902. 319 interactions. |
|
There are currently no product reviews
|
.png "ACE2/HEK293 Stable Cell Line")
