Polyclonal Antibody to MRF2
Fig-1: Expression analysis of MRF2. Anti-MRF2 antibody (11-12017) was used at 1 µg/ml on HCT-116 lysate.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Rabbit IgG |
| Purification : | Protein A Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles. |
MRF2 (Modulator Recognition Factor-2) is a member of the ARID (AT-Rich Interaction Domain) family of transcription factors. The ARID defines a highly conserved sequence specific DNA binding domain and has been identified in proteins of yeast, Drosophila, and mammals. MRF2 is essential for accumulation of lipid stores in postnatal life. MRF2 is highly expressed in the aorta, heart, lung, small intestine, kidney, muscle, and brain.
Western blot analysis: 1-2 µg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Nucleus |
| Post transnational modification: | Methylation at Lys-336 prevents DNA-binding. Demethylation by PHF2 promotes recruitment of the PHF2-ARID5B complex to promoters. |
| Tissue Specificity: | Widely expressed, including in liver (at protein level). |
| BioGrid: | 123918. 20 interactions. |
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