Polyclonal Antibody to DLL1
Figure-1: Expression analysis of DLL1. Anti-DLL1 antibody (11-10034) was used at 1 µg/ml on h Heart lysate.
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| Format : | Purified |
| Amount : | 100 µg |
| Isotype : | Rabbit IgG |
| Purification : | Protein A Chromatography |
| Content : | 25 µg in 50 µl/100 µg in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic. |
| Storage condition : | Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles. |
DLL1 (Delta-like 1) is a human homolog of the Drosophila Notch ligand Delta that is the ligand for Notch3. It belongs to the family of Notch ligands and Notch signaling is one of the most conserved pathways in the regulation of cell differentiation and cell fate decisions. DLL1 is expressed in a goblet cell-specific manner in human colonic tissue. DLL1 like notch ligands are known to selectively drive antigen-specific CD4 T helper 1 cell responses which are important in protective immune response in leishmaniasis.
Western blot analysis: 1-2 µg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Apical cell membrane, Cell junction, Membrane raft |
| Post transnational modification: | O-fucosylated. Can be elongated to a disaccharide by MFNG. |
| Tissue Specificity: | Expressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney. |
| BioGrid: | 118391. 5 interactions. |
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